Weill Cornell Medicine Urology
Weill Cornell Medicine Urology
Testis Cancer - Risks & Causes

Testis Cancer - Risks & Causes

Find a Physician

FIND A PHYSICIAN

Quickly search our world-class physicians and faculty by keyword, location and insurance provider.

Search

Cryptorchidism (or undescended testis) can increase the risk of developing cancer in the affected testis, as well as the opposite testis, even if it is normally descended. The degree to which surgical correction of cryptorchidism (called "orchidopexy") can decrease this risk has not been determined, although there appears to be a protective effect when surgery is performed prior to puberty.

Individuals who have had testis cancer in one testis have about a 3-4% chance of developing cancer in the opposite testis. All individuals who have a history of cryptorchidism or testis cancer require lifelong surveillance by examination. White men versus Black and Asian men have a four- to five-times higher risk for developing testis cancer. Evidence for other risk factors has been lacking. Although patients often report a history of preceding testicular trauma, this event usually leads to self-examination and incidental discovery of a mass that is not associated with the trauma.

HIV patients have a greater risk of developing other tumors such as lymphoma and sarcoma that can affect the testes; however, these patients' risk of GCT appears to be the same as seen in the overall population.

Patients with Klinefelter's syndrome are at greater risk of forming GCT outside of the testes, notably inside the chest (mediastinum). Exposure of pregnant women to diethylstilbesterol (DES) appears to increase the incidence of testis cancer in their male children. However, the effect of DES on adult men does not appear to increase the risk of developing testis cancer.

Some have proposed that increased scrotal temperature, which may occur in those with a sedentary lifestyle, may be a putative factor in the formation of testicular neoplasia. Investigations thus far are inconclusive.

Find a Physician FIND A PHYSICIAN

Physicians & Faculty

Dr. Peter N. Schlegel, MD, FACS | Cornell Urology

Peter N. Schlegel

M.D., F.A.C.S.

212.746.5491
212.746.5491
Aetna-Weill Cornell POS, Medicaid, Medicare, Rockefeller University-CoreSource
The LeFrak Center for Robotic Surgery
Dr. Marc Goldstein, M.D., F.A.C.S. | Weill Cornell Medicine

Marc Goldstein

M.D., F.A.C.S.

212.746.5470
212.746.5470
Aetna-Weill Cornell POS, Medicaid, Medicare, Rockefeller University-CoreSource
Brady Urologic Health Center

Jim C. Hu

M.D., M.P.H.

(646) 962-9600
(646) 962-9600
AETNA [Medicare], AETNA-HMO, AETNA-PPO, Aetna-Weill Cornell POS, Affinity Access, Affinity Essential, Affinity Health Plan, Blue Priority Network, CIGNA, EBCBS HMO, EBCBS Mediblue, EBCBS Pathway X, EBCBS Pathway X Enhanced, EBCBS PPO/EPO, Emblem Select Care, Empire BCBS HealthPlus, Empire BCBS HealthPlus (CHP), Fidelis Care, GHI, Health First, Health Insurance Plan of NY (HIP), Health Insurance Plan of NY (HIP) [Medicaid], Health Insurance Plan of NY (HIP) [Medicare], Medicaid, Medicare, Oxford Freedom, Oxford Health Plans [Liberty], Oxford Health Plans [Medicare], Oxford Health Plans [Metro/Core/Charter], POMCO, Rockefeller University-CoreSource, UHC Community Plan - Essential Plan, UHC Community Plan - Medicaid Plan, UHC Compass-HMO, UHC Medicare, United Empire Plan, United Healthcare Commercial, VNSNY CHOICE Medicare, VNSNY CHOICE SelectHealth
The LeFrak Center for Robotic Surgery
Dr. David Michael Nanus, M.D.

David M. Nanus

M.D.

646.962.2072
646.962.2072
AETNA [Medicare], AETNA-HMO, AETNA-PPO, Aetna-Weill Cornell POS, Affinity Health Plan, CIGNA, EBCBS HMO, EBCBS Mediblue, EBCBS PPO/EPO, GHI, Health Insurance Plan of NY (HIP), Health Insurance Plan of NY (HIP) [Medicaid], Health Insurance Plan of NY (HIP) [Medicare], Oxford Health Plans [Liberty], Rockefeller University-CoreSource, United Empire Plan, United Health Care, United Health Care [Community Plan]
Dr. Douglas S. Scherr, M.D. | Weill Cornell Medicine

Douglas Scherr

M.D.

212.746.5788
212.746.5788
AETNA [Medicare], AETNA-HMO, AETNA-PPO, Aetna-Weill Cornell POS, CIGNA, EBCBS HMO, EBCBS Mediblue, EBCBS PPO/EPO, Empire BCBS HealthPlus, Empire BCBS HealthPlus (CHP), GHI, Health Insurance Plan of NY (HIP), Health Insurance Plan of NY (HIP) [Medicare], Medicaid, Medicare, Rockefeller University-CoreSource, United Empire Plan, United Healthcare Commercial
Brady Urologic Health Center
Dr. Scott T. Tagawa, M.D., MS

Scott T. Tagawa

M.D.

646.962.2072
646.962.2072
AETNA [Medicare], AETNA-HMO, AETNA-PPO, Aetna-Weill Cornell POS, Affinity Access, Affinity Health Plan, Blue Priority Network, CIGNA, EBCBS HMO, EBCBS Mediblue, EBCBS Pathway X, EBCBS PPO/EPO, Emblem Select Care, Empire BCBS HealthPlus, Empire BCBS HealthPlus (CHP), Fidelis Care, GHI, Health First, Health Insurance Plan of NY (HIP), Health Insurance Plan of NY (HIP) [Medicaid], Health Insurance Plan of NY (HIP) [Medicare], Medicaid, Medicare, Oxford Freedom, Oxford Health Plans [Liberty], Oxford Health Plans [Medicare], Oxford Health Plans [Metro/Core/Charter], POMCO, Rockefeller University-CoreSource, UHC Compass, United Empire Plan, United Health Care, United Health Care [Community Plan], United Healthcare Commercial, VNSNY CHOICE Medicare, VNSNY CHOICE SelectHealth
Dr. Himisha Beltran, M.D.

Himisha Beltran

M.D.

212.746.5449
212.746.5449
AETNA [Medicare], AETNA-HMO, AETNA-PPO, Aetna-Weill Cornell POS, CIGNA, EBCBS HMO, EBCBS Mediblue, EBCBS PPO/EPO, Health First, Health Insurance Plan of NY (HIP), Health Insurance Plan of NY (HIP) [Medicaid], Health Insurance Plan of NY (HIP) [Medicare], Oxford Freedom, Oxford Health Plans [Liberty], Oxford Health Plans [Medicare], Rockefeller University-CoreSource, United Empire Plan, United Health Care, United Health Care [Community Plan]
Multimedia

Multimedia

© 2016 Weill Cornell Medicine All rights reserved.