Dr. Peter Schlegel, Chairman of Urology at Weill Cornell Medicine, was featured in Newsweek, discussing the potential for a male birth control pill that would temporarily stop sperm production. Dr. Schlegel comments on recent research that lays a "genetic foundation for male birth control" in an animal study. He also explains some of the biological barriers that make the development of a male birth control pill a complex task:
Marc Goldstein, MD, DSc (hon), FACS discusses his role as a urologist, surgeon and pioneer in male infertility evaluation and treatment at Weill Cornell Medicine/NewYork-Presbyterian Hospital in New York City. To make an appointment with Dr. Goldstein in NYC, please call his office at (212) 746-5470. For more information on Dr. Goldstein, please visit: http://urology.weillcornell.org/marc-goldstein
A fertility evaluation is often pursued in couples who have not been able to conceive for a period of 6-12 months of unprotected intercourse. A fertility evaluation may be appropriate sooner than this when the couple is considered to be at higher risk for subfertility or infertility: when the female partner is over age 35; when there has been a history of infertility in a prior relationship; or when there are other risk factors which may cause fertility problems (e.g. cryptorchidism, testicular neoplasm, chemotherapy, radiation therapy).
The human male reproductive system includes hormonal and structural components. These components include the hypothalamic-pituitary-testis axis as well as the epididymis, vas deferens, seminal vesicles, prostate and urethra. Production of spermatozoa requires approximately 3 months from the initial duplication of stem cells that are supposed to develop into sperm, through mitotic divisions and the myriad changes that modify sperm, preparing them for ejaculation and fertilization.
Our NIH funded laboratory has received generous support from private foundations and donors. Their significant contributions allow us to better understand male infertility, reproductive medicine, and other urologic conditions.
Infertility is defined as a couple's inability to achieve pregnancy following one year of appropriately timed and unprotected intercourse. By this criterion it has been estimated that approximately 15 to 20% of couples attempting to achieve pregnancy are unable to do so. A female factor is the primary etiology in approximately 50% of these couples, and another 20 to 30% are pure male factor. A combination of male and female factors accounts for the remaining 20 to 30% of cases.